Dysport vs. Botox vs. Xeomin vs. Letybo: Which Is Right for You?

They all smooth lines by relaxing the same muscles, but they are not identical. Because Melange Spa carries several, here is an honest comparison to help you choose.

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They all smooth lines by relaxing the same muscles, but they are not identical. Because Melange Spa carries several, here is an honest comparison to help you choose.

They all do the same core job

Neuromodulators (often called "Botox" generically, after the first brand) are purified proteins that temporarily relax the muscles responsible for dynamic wrinkles, forehead lines, frown lines, and crow's feet. The result is a smoother, still-expressive look. The differences between brands are real but subtle.

Onset and spread

Dysport tends to kick in quickly and spreads a little more, which makes it efficient for larger areas like the forehead. Xeomin is a "naked" formulation with no added proteins, which some patients prefer. Jeuveau is a modern cosmetic-focused option, and Letybo is a newer, value-friendly choice. Your injector will factor in how fast you want to see results and how precise the placement needs to be.

Longevity

For most people, results from any of these last about 3 to 4 months. Longevity depends more on your metabolism, dose, and muscle strength than on the brand. Consistent maintenance visits often make each subsequent treatment last a little longer.

Cost at Melange Spa

Our per-unit pricing is Letybo $9, Jeuveau $10, Xeomin $10, and Dysport $12. Because Dysport is dosed in different units than the others, the best way to compare is total cost for your specific areas, which we estimate at your visit. See our full injectables page for details.

How we choose with you

There is no single "best" neuromodulator, only the best fit for your face, goals, and budget. We talk through your priorities, look at how your muscles move, and recommend accordingly. Treatments are performed only by licensed medical professionals.

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Questions

Frequently asked

Which neuromodulator lasts the longest?

For most patients all four last about 3 to 4 months. Longevity depends more on your dose, metabolism, and muscle strength than on which brand you choose.

Is Letybo as good as Botox?

Letybo is an FDA-approved neuromodulator that works the same way. Many patients choose it as a strong value option; your injector will help you decide based on your goals.

Can I switch brands between visits?

Yes. Switching is common and safe, and sometimes we adjust the brand based on how you responded last time.

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